Welcome to Lewis and Clark’s
Lewis and Clark’s, located in St. Charles, MO, offers a historical ambiance with outdoor seating and a full bar. The menu boasts American cuisine with options like Cajun sandwiches, white bean chicken chili, and Teriyaki Chicken Breast Sandwich. Customers praise the friendly service and diverse drink selection, with highlights including a Prosecco and pineapple cocktail and red wine sangria. While some dishes received mixed reviews, the overall consensus is positive, making Lewis and Clark’s a solid choice for food and drinks with friends on Main Street. I look forward to revisiting to explore more of their menu offerings.
- 217 S Main St St Charles, MO 63301 Hotline: (636) 947-3334
Lewis and Clark’s is a renowned American restaurant located in St. Charles, MO, offering a variety of dining experiences to its patrons. This establishment takes pride in its ability to cater to a diverse range of preferences, from offering limited vegetarian options to providing a full bar with a selection of beverages. With amenities such as outdoor seating, free Wi-Fi, and waiter service, Lewis and Clark’s ensures a comfortable and enjoyable dining experience for all guests.
Customer reviews have highlighted the friendly and communicative staff at Lewis and Clark’s, making each visit a pleasant and memorable one. Dishes like the chicken apple and bacon quesadilla, prime rib, cajun sandwich, and teriyaki chicken breast sandwich have received praise for their flavors and generous portions. The extensive menu at Lewis and Clark’s ensures that there is something for everyone to enjoy.
The ambiance of the restaurant, with its historic charm and outdoor seating options, adds to the overall dining experience. Whether you visit for lunch, dinner, or simply to enjoy a cocktail at the bar, Lewis and Clark’s offers a welcoming atmosphere for all occasions. If you find yourself in St. Charles, be sure to stop by Lewis and Clark’s for a delicious meal and excellent service.

After looking around here and see some restaurants closed on New Year Day but this place Lewis and Clark is open. Friend wanted to try this place. Noticed this is 3 stories restaurant seatings. Waitress is friendly and communicate well with us. I ordered chicken apple and bacon quesadilla. It was good with blue cheese dressing. Friend ordered prime rib. He wanted medium well but he got medium rare. He said it was good. I'd come back again

This is a great spot to stop for food when on Main Street. Great selection of both lunch and dinner options. Bar seating is a good option if you're looking for a quick meal in between shopping.

Lewis and Clark's used to be our favorite restaurant years ago but like many things we changed our routine and haven't been back to eat for some time . We got a table on the 3rd floor outside overlooking Mainstreet and had a great dinner! The cajun sandwich with red beans and rice was just as delicious as I remembered! The white bean chicken chili was perfect! I hope to be back more often!

Had lunch here with mom and daughter. We were seated on the open air porch. Our server was friendly and the atmosphere was nice. I had salad and 1/2 club sandwich, mom had salad and soup and my daughter had kids chicken tenders. The kids chicken tenders was a generous portion. Club sandwich was excellent as was the salad. Everything was great. I would return.

I recently visited Lewis and Clark's with a group of five friends for Fourth of July. The experience was overall pleasant. No complaints about the service! Our server was friendly and attentive, making sure our drinks were always full. The restaurant itself was clean. The drinks were definitely the best part. I tried a cocktail made with Prosecco and pineapple juice, which was delicious and quite strong. I also had their red wine sangria, and both drinks were beautifully garnished with fresh fruit. If you're looking for a place to enjoy a variety of alcoholic beverages options, this is a solid choice. As for the food, I ordered the Teriyaki Chicken Breast Sandwich. The flavor was average; it wasn't anything special. My biggest issue was that the sauce and grilled pineapple made the bun extremely soggy, so I ended up eating it without the bread. However, I do like that the menu has a wide variety of food options, so there's a little something for everyone. Lewis and Clark's is a decent spot to grab food and drinks with friends. The drinks are definitely worth trying, but the food didn't necessarily "wow" me.

This restaurant is on Main St. in St. Charles. It was nice to sit outdoors on the balcony. The venue displays a historic feel. The food was good and the service was fine. I had the blacken chicken with salad for lunch and a piece of cheesecake for dessert. We really enjoyed sitting outdoors which made our afternoon taking in some sun. I would return and try something else on the menu.